• chewypoops@lemmy.world
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    6 hours ago

    I know that most people describe these hallucinations as unpleasant, but I do kinda want to know. I wanna meet those little guys.

  • DanceMomsSavedMe@lemmy.zip
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    8 hours ago

    Can’t wait for it to become known so governments all across the world can throw you in a prison cell and ruin your life for it like the other known hallucinogens.

      • douglasg14b@lemmy.world
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        5 hours ago

        If you don’t know what you’re talking about, why comment at all? Get that shit out of here and go back to Reddit with it.

      • bloogoose@lemmy.zip
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        5 hours ago

        Spoken like a 22 year old who grew up in a conservative household and never needed to think beyond what others have told them.

      • partofthevoice@lemmy.zip
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        6 hours ago

        Is that how you justify telling other people how they’re allowed to spend their time? You just have to presume that their life is (1) in danger, (2) at their own fault, (3) and it’s your responsibility to do something, (4) even against their own will—and you can just apply this rubric of thought to any particular discontent with their character? How convenient. So, if you don’t like gay people, should you also teach thy neighbor about god? Maybe force them to read the bible in a conversion camp? It sure would be better if everyone thought just like us, huh?

        • fxdave@lemmy.ml
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          4 hours ago

          I think you’re talking about adults, otherwise it wouldn’t be a question that yes, you should save them from themselves.

          Talking about adults, haven’t you seen videos about countries where they allowed every drugs? Have you ever bought a product and disappointed in it despite the PR and research you put in? Have you ever bought a product without research? No, people can’t decide responsibly, they learn from their fault when it’s too late. The market needs to be green.

          • partofthevoice@lemmy.zip
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            2 hours ago

            I have a rather interesting view on the matter. Typically even my in-group doesn’t agree with me on this. Yet I think all drugs should be legal. Access to drugs should be strictly regulated (imo), but easy. Therapists should be able to obtain license to administer psychedelics. There should be therapeutic centers specializing in use of psilocybin, ketamine, and MDMA. There should be other types of therapeutic centers where you can get access to methamphetamine, opioids, and other drugs—as prescribed necessary for addiction treatment. There should be places to buy recreational drugs like cannabis.

            Everything has a place, in my view. Banning something outright is naive, creating more problems in the long run. If you swap from enforcement of prohibition to a more utilitarian approach, you can get a lot more done. That doesn’t mean you give drugs away and create addicts. It means you be a grown up and stop acting like everything is the boogie man, while also acting like anyone who touches it has caught cooties.

            People do a pretty good job policing themselves when the system is established in a manner to empower them with good choices. It’s the same idea as the panopticon, as old as Jeremy Bentham, but in reverse. People aren’t going to go get their free meth when culturally it’s known to be for addicts who are at a bad place in life. People who do just want free meth are now surrounded by psychologists who can help.

            • fxdave@lemmy.ml
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              1 hour ago

              There are some social crises in people life where policing themselves gets lower focus e.g. on a break up. I think the easy access is the problem. And to fix it with opening it up even more is not a good idea.

              I would give people money if they can tell who is a dealer. So the market itself would fix the problem.

              • partofthevoice@lemmy.zip
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                25 minutes ago

                Easy access isn’t the problem and hasn’t even been tried. There isn’t easy access. There’s illegal access through shady networks with unverified merchants and products. That’s the result of the prohibition… that and decades of a stupid war on drugs.

                “Opening it up more” presumes that I mean “give more people more access to more drugs in the same way they do now.” That’s not at all what I mean.

                There are some social crises in people life where policing themselves gets lower focus

                Sure. Then they can just go to their local gas station drug dealer and buy some meth then. Your solution doesn’t seem much better. I don’t see how this really argues against a utilitarian approach to drug regulation.

          • NιƙƙιDιɱҽʂ@lemmy.world
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            3 hours ago

            There is not a single country where every drug is “allowed,” wtf are you talking about?

            This is such “I’m 17 and grew up in a conservative household” energy. How did you even end up on Lemmy?

            • fxdave@lemmy.ml
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              2 hours ago

              If you’re interested I’m 29 and born in a hungarian village where nobody was religious. I ended up on lemmy because I am a developer and free software supporter. I want a nice place to live in, and psychedelics does not fit into that picture.

              Maybe just accept that not everybody has the same opinion. Let me express that I think psychedelics should be banned.

              I have to correct myself, it’s not a country, it’s a city Portland. https://youtu.be/2GU3TGSWPsw?is=5lJ-PJ44vzzfmCfM

  • CheeseNoodle@lemmy.world
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    11 hours ago

    Potentially (potentially doing a LOT of heavy lifting here) unethical, make a reasonably comfortable tiny person cell, take the mushrooms, put a tiny person in the cell. A second person who is completely unaware of the previous events takes the mushroom and we see if they can see the same tiny person still in the cell.

  • rizzothesmall@sh.itjust.works
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    15 hours ago

    they found no close matches to genes associated with psilocybin or ibotenic acid, two well-known mushroom hallucinogens

    None that we already know about, not the same as none

  • SunshineJogger@feddit.org
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    16 hours ago

    No matter what it is, it is fascinating in its own right that it has such a specific visual effect on users.

    Maybe this mushroom was very common once and is the source for folk tales of all sorts.

    I mean there are truly a lot of old stories involving tiny people.

    • mPony@lemmy.world
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      3 hours ago

      There are also a lot of old stories about people seeing tall slender alien-like creatures. I wonder if there’s a substance that causes that.

  • frongt@lemmy.zip
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    1 day ago

    “Biosynthetic gene mining of the L. asiatica genome found no close hits with any genes known in the production of mushroom psychoactive compounds,” write the researchers in their published paper.

    “This supports our hypothesis of the presence of a novel unidentified metabolite responsible for the unique hallucinogenic properties of L. asiatica.”

    Yeah. No known hallucinogens.

    • DougPiranha42@lemmy.world
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      1 day ago

      Exactly. Or even- no known hallucinogens synthesized by their canonical biochemical pathways by enzymes expressed from the host species genome.
      The OG hallucinogen, ergot, is ingested by eating wheat. If one presumed that the substance is made by wheat, and mined the wheat genome, they would never find the genes for its synthesis, because the hallucinogen is made by mold growing on the wheat.
      It’s very rare you can draw a strong conclusion from negative results.

      • boydster@sh.itjust.works
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        1 day ago

        Rye is the most common place ergot grows, which is another common bread grain. I am not disagreeing with your post, and ergot can grow on wheat too, just pointing out that rye is a much more common source of egot contamination.

        • webghost0101@sopuli.xyz
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          17 hours ago

          I dont really know these things but i always just assumed rye (and barely) was just a kind of wilder less domesticated wheat.

  • WoodScientist@lemmy.world
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    1 day ago

    Maybe it’s not a hallucination at all. Maybe the mushroom is actually an anti-hallucinogen. It suppresses the hallucinations that normally prevent us from seeing the tiny people.

    • webghost0101@sopuli.xyz
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      17 hours ago

      It doesn’t need to be, there is reasonable proof that humans and other mammals naturally synthesises (trace amounts off) dmt, which are presumed to be used and broken down incredibly quickly. We still don’t know why, what its used for or have hard proof where its produced (pineal gland is main suspect for having all ingredients in theory)

      In theory something could trigger an effect that stops it from breaking down or produce it at a faster rate, therefore triggering psychedelics effects with out the consumed substance containing anything psychedelic itself.

      Dmt is known for seeing (machine) elves, does not sound that far away from seeing mini people.

  • gnufuu@lemmy.ca
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    1 day ago

    Lanmaoa asiatica

    My sincerest apologies. I know the way out.

  • rain_enjoyer@sopuli.xyz
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    1 day ago

    Clickbait headline, the primary object of that study was to figure out phylogeny of these mushrooms. finding no known genes associated with known hallucinogens is a bonus and pretty useless info because the compound responsible for this activity is not known, how do you know how it’s made then

  • GreyShuck@feddit.uk
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    1 day ago

    Regardless of the actual metabolite responsible, this does raise the question of whether, if any other species consume them and are susceptible, they see tiny versions of their own species?

    • magnue@lemmy.world
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      1 day ago

      I always wonder if the cows get high. On the right day it’s like daisies in summer and they’re just munching grass all day.

      • Donkter@lemmy.world
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        23 hours ago

        The psylocibin mushroom specifically grows on cow shit so some of them have to be getting dosed at some point.

      • Catoblepas@lemmy.blahaj.zone
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        1 day ago

        Monkeys seem like a good place to start. Similar enough to us to see if it’s unique to humans, small enough to not start ripping someone’s face off if it goes badly.

          • DougPiranha42@lemmy.world
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            1 day ago

            Mackaques love touchscreens, amd can be trained to do complex tasks on tablets placed in their enclosures.
            You make a test where they need to press a button when and only when they see tiny monkeys that you can project on a screen or on their floor.
            Then you give the drug at various concentrations and placebo, and see if there is a dose dependent increase in the monkeys indicaions of mini monkeys.
            Then you can repeat the experiment after treatment with antipsychotic, if it prevents the mini monkey reporting, you already have a hint at the mechanism.
            Any nonhuman primate lab can do this from 1-2 million dollars, should we start a go fund me?

          • Danarchy@lemmy.nz
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            1 day ago

            Get one of them sign language moneys and see if they start asking for tiny bananas

          • AlteredEgo@lemmy.ml
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            1 day ago

            Can’t you just ask them? Like train them to show what they are seeing by pointing to one of multiple pictures.

          • Gerudo@lemmy.zip
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            1 day ago

            I think you could watch pupil response, body temp, sweating, brain scans, etc and get a good idea.

              • vala@lemmy.dbzer0.com
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                9 hours ago

                Monkey brain scan will change depending on what it sees. Monkey sees humans vs monkey sees monkey is a very different looking scan result.

                • cynar@lemmy.world
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                  5 hours ago

                  Trying to scan a monkey’s brain, while it’s awake and interacting is not a trivial task. MRI scanners are uncomfortable for humans, and we know what is going on with the big scary machine.