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Cake day: January 20th, 2026

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  • Mackaques love touchscreens, amd can be trained to do complex tasks on tablets placed in their enclosures.
    You make a test where they need to press a button when and only when they see tiny monkeys that you can project on a screen or on their floor.
    Then you give the drug at various concentrations and placebo, and see if there is a dose dependent increase in the monkeys indicaions of mini monkeys.
    Then you can repeat the experiment after treatment with antipsychotic, if it prevents the mini monkey reporting, you already have a hint at the mechanism.
    Any nonhuman primate lab can do this from 1-2 million dollars, should we start a go fund me?



  • I doubt that the median adult in any country would have a grasp of core concepts of physics, chemistry and biology. Yes, everyone hears about it in school, and then they forget; and that knowledge gets replaced by the pseudoscience babble oozing from mass media and from phonies selling things like homeopathy, creationism, antivaxx, chemtrail, astrology, aliens, conspiracies and such. Exposure to these undermines people’s ability to ground their world view in scientific principles.
    You may remember your science education because you are in a stem field and your everyday way of thinking is grounded in science. But that doesn’t mean everyone else does too. Don’t fall into the “common knowledge is whatever I know“ fallacy.




  • I’m in Neuroscience. My favorite way to keep up is rss feeds of the 5 best journals (100-200 titles per week), rss feeds to the relevant pubmed search terms (20-50 titles per week) an google scholar email alerts to some of the most relevant researchers in my field, auto forwarding to kill the newsletter, and read through rss (50-100 titles per week, lots of duplicates). So every day I aim to open the rss reader and burn down the unread count. Papers that are really relevant to my research tend to show up 4-5 times over 2 weeks this way, so it’s hard to miss it. Which journals: you know that if you have been in the field for a while, if not, ask your colleagues and mentors where they publish and what they read.
    Bad papers sliding through the cracks: it happens, you don’t know unless you read it.