• DougPiranha42@lemmy.world
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      22 hours ago

      Mackaques love touchscreens, amd can be trained to do complex tasks on tablets placed in their enclosures.
      You make a test where they need to press a button when and only when they see tiny monkeys that you can project on a screen or on their floor.
      Then you give the drug at various concentrations and placebo, and see if there is a dose dependent increase in the monkeys indicaions of mini monkeys.
      Then you can repeat the experiment after treatment with antipsychotic, if it prevents the mini monkey reporting, you already have a hint at the mechanism.
      Any nonhuman primate lab can do this from 1-2 million dollars, should we start a go fund me?

    • Danarchy@lemmy.nz
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      22 hours ago

      Get one of them sign language moneys and see if they start asking for tiny bananas

    • AlteredEgo@lemmy.ml
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      23 hours ago

      Can’t you just ask them? Like train them to show what they are seeing by pointing to one of multiple pictures.

    • Gerudo@lemmy.zip
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      24 hours ago

      I think you could watch pupil response, body temp, sweating, brain scans, etc and get a good idea.

        • vala@lemmy.dbzer0.com
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          5 hours ago

          Monkey brain scan will change depending on what it sees. Monkey sees humans vs monkey sees monkey is a very different looking scan result.

          • cynar@lemmy.world
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            1 hour ago

            Trying to scan a monkey’s brain, while it’s awake and interacting is not a trivial task. MRI scanners are uncomfortable for humans, and we know what is going on with the big scary machine.