The faked line of research was regarding Lesne’s line of papers on a specific amyloid beta protein configuration AB*56
Proteins can be folded in any number of shapes, any of which can have different effects.
The OP’s article states:
The blood test uses high-resolution mass spectrometry to measure the ratio of levels of amyloid (Aβ42 and 40) and two forms of tau protein (p-tau217 and total tau217) in the blood. These biomarkers are associated with amyloid pathology, a characteristic feature of Alzheimer’s disease.
As a layman, I see there’s a difference between AB 42/40 and AB 56
That’s a huge exaggeration of what the article you linked to says https://www.science.org/content/blog-post/faked-beta-amyloid-data-what-does-it-mean
The faked line of research was regarding Lesne’s line of papers on a specific amyloid beta protein configuration AB*56
Proteins can be folded in any number of shapes, any of which can have different effects.
The OP’s article states:
As a layman, I see there’s a difference between AB 42/40 and AB 56