In the realm of medical advancements, a universal vaccine that can protect against any pathogen has long been a Holy Grail—and about as elusive as a mythological vessel. But Stanford Medicine researchers and collaborators have taken an astonishing step forward in that quest, surprising even themselves.
But how does this make dust mite allergy better and not worse?
Yeah, an overly heightened immune system is how you get allergies and auto-immune diseases.
I’m working on getting (ok, it’s just arrived, and I need to head off to class) and digesting the paper. I suspect that this is because of the more effective application/regulation of macrophages, CD4+ and CD8+ cells, such that they aren’t over responsive. To keep with the metaphor above, the TRMs are in a dormant state, waiting to be activated, but in this case the activation is much more specific, so it’s not going ‘off the rails’ for every Hombre with a Black Hat, but rather every Hombre with a Black Hat, leather hat band, and a white feather, sort of. I’ve not read beyond the Abstract.
So each season it would be tuned to “what was in fashion” for the expected coming cold/flu season?
That sounds awesome.
Shot up the nose for a chance to miss the worst bug of he seasonm I would take those odds! (And yes, I’m aware of and partake of the bargain that is existing annual flu shot, haha.)
The same way allergen injections can reduce an allergic response. It’s one type of antibody and focusing a response will remove the antibody from circulation and allergy elsewhere.
But this is just mice, any claims on human allergy is bullshit. Regardless, either this research is dead because the NIH is gone, or this has moved to a biotech, so this is hype for VC investment.